Posts Tagged ‘Vitamin D3’
I was told last week about the mother of an acquaintance in Chicago. His mother has had Vertebral Fractures again and again and again. After each fracture she has been told that nothing can be done to prevent another vertebral fracture. She is turning into a pretzel as her spine crumbles.
After 2 vertebral fractures, she is odds on favorite to fracture another vertebra within the year. She is also unlikely to respond well to an antiresorptive such as Fosamax, Actonel, Boniva, Reclast, Prolia or their generics because of her severe osteoporosis. Game over? Not at all.
Multiple vertebral fractures make her an ideal candidate for an anabolic medication. Forteo (2002), Tymlos (2017), and Evenity (2019) all can salvage her bone health and increase her bone matrix by 20% or more. I recommended she see someone up to date in the options available. There are several in Chicago. And several here in Iowa.
She needs a Complete Bone Health Evaluation and anabolic treatment. Of course that includes enough absorbable calcium, enough Vitamin D3, and other nutrition. Anabolic medications specifically require enough protein to work because they build new bone matrix, which is collagen, which is protein.
You don’t have to fracture again and again. We can help.
Jay Ginther, MD
Fathers Day is a time to remember your Dad. Those young enough and fortunate enough to have a living Dad today should take time to connect and honor him, even if the best available is waving through a window or using Zoom. Even if he is gone, take time to remember the good times and what he got right. Repeat those yourself.
Wish your Dad a fulfilling and healthy life. Avoid unnecessary problems, like fractures. One in four men over 50 will have osteoporosis and unnecessary fractures unless they are treated for their osteoporosis. Most fractures are a major inconvenience. The majority of hip fractures in men over 70 result in complications leading to death or nursing home.
Detect osteoporosis early to start treatment to prevent fractures. In many cases the only treatment necessary is improved nutrition and lifestyle.
Start with a Complete Bone Health Evaluation. That includes DXA/VFA, blood tests, focused history and physical, and focused consultation.
We find major and minor nutritional issues. We help Dad correct them with enough calcium, vitamin D3, protein, other vitamins and minerals.
Improved lifestyle can improve diabetes, high blood pressure, strength, balance, and overall enjoyment of life.
Really care for your Dad by helping him to a happier, healthier life. Help him Take Control of his future.
Jay Ginther, MD
Today I ran across mention of an old observational study of seasonal colds and flu in northern (temperate zone) and southern (tropics) India. Colds and flu had no seasonality in southern India where vitamin D from sunshine is equally available all year.
Colds and flu were seasonal in northern India closely following the months when vitamin D is not readily available from the sun which is too low on the horizon to produce vitamin D. There is not direct evidence that lower vitamin D levels allow more colds and flu, but it seems reasonable.
We have long known that vitamin D is involved in human immune system function as well as bone health. e.g. A National Institute of Health study found that persons with monohydroxy-vitamin D levels over 33ng/ml have half the risk of colorectal cancer as those with less than 12 ng/ml.
Vitamin D toxicity is possible but very rare according to the Mayo Clinic, requiring doses of 50,000 IU (1250 mcg) daily for months.
My experience in Iowa is that most persons not taking at least 1000-2000 IU (25-50 mcg) daily have vitamin D levels below 20ng/ml December through April. That is also cold and flu season.
I take 5000 IU (125 mcg) daily to keep my level at 50-60 ng/ml. That can’t hurt and it might help prevent viral infections. Over age 65, I have started working from home and am setting up TeleMedicine capabilities because of COVID-19 guidelines.
Follow your state’s health department guidelines. And extra vitamin D could help. If you have not taken any in the past, up to 5000 IU (125 mcg) daily should be safe until you have a chance to check your level.
Jay Ginther, MD
National Bone Health treatment goals are changing for those patients with high fracture risk. Simply preserving bones already at a too high fracture risk never made much sense to this former orthopedic surgeon. Now the national leadership is stressing the need to lower fracture risk first, then preserve bones at a lower level of fracture risk.
We now have 3 anabolic medications which substantially lower fracture risk by increasing the thickness and strength of bone structure: Teriparatide (Forteo), Abaloparitide (Tymlos), and Romosozumab (Evenity). They all decrease fracture risk substantially more than the antiresorptive (preserving) medications alone. The difference in fracture risk grows for up to 5 years. After that the difference in fracture risk between anabolic meds followed by preserving meds vs. preserving meds alone remains the same.
Calcium can take up to 3 additional years to collect in newly formed bone matrix. DXA shows calcium in bone (Bone Mineral Density). Much of the increased BMD can only be seen on DXA after the anabolic med is completed and the antiresorptive med is started.
All of the anabolic medications must be followed by antiresorptive medication to preserve the gains made by the anabolic. No medication to grow or preserve bone can work without adequate nutrition in the form of absorbable calcium, vitamin D3, protein and other vitamins and minerals.
Jay Ginther, MD