Posts Tagged ‘Prolia’
Anabolic medication for osteoporosis actually increases bone thickness and strength! Antiresorptive medications for osteoporosis (Fosamax, Alendronate, Actonel, Atelvia, Boniva, Evista, Reclast, Prolia) only preserve bone.
We have talked about all of the Antiresorptive medications over the last 2 months. They are excellent treatment if slowing down the OsteoClasts (cells that eat away your bone) is sufficient. That is not always the case.
Now it is time to talk about something completely different. Anabolic medication stimulates the OsteoBlasts (cells that make new bone matrix). OsteoBlasts can rebuild your bones. If you have Fractures, your bones may need to be rebuilt.
Forteo (Teriparatide) is the only Anabolic medication for osteoporosis in the USA. Close cousins of Forteo are available in other countries.
You may need the Anabolic, Forteo, if you have a hip fracture, multiple other fractures, or if VFA testing reveals a Vertebral Compression Fracture. A DXA T-score well below -2.5 can be reason enough without fracture.
Glucocorticoid (Cortico-Steroid) medications (Prednisone, Steroid Inhalers) specifically supress OsteoBlasts (cells that make new bone). Stimulating the OsteoBlasts with the Anabolic, Forteo, can offset the bone loss from Steroid medications. Smoking also supresses OsteoBlasts, leading to bone loss. Stopping Smoking would be best, but Forteo can help.
Not everyone needs an Anabolic, but some individuals do. A Complete Bone Health Evaluation will tell you if an Anabolic is right for you.
More about Forteo (Teriparatide) next time.
Jay Ginther, MD
Aunt Henrietta’s 90th birthday party was a triumph. Over 100 friends, neighbors, and relatives attended. She planned and arranged it all herself. This was not the feeble 89 year old of last fall. This was the comeback kid.
6 years ago Henrietta had fallen and broken both wrists and a shoulder in 3 separate incidents. That was before she took Forteo, followed by Prolia. Last year she was sick enough to be falling several times a day. But she did not break anything! Had she broken she would probably not have celebrated her 90th.
Aunt Henrietta waited until age 83 to start taking enough Calcium (Adora Premium Chocolates), enough Vitamin D, and almost enough Protein. Then she waited until she had fractured both wrists and a shoulder before starting osteoporosis medication.
I am not happy that she still falls ocassionally in her 3 level house, but I know that now she doesn’t break anything.
Aunt Henrietta is a triumph.
You don’t have to wait as long as she did to check up on your bone health. Get a Complete Bone Health Evaluation.
Take Control of your future now.
Jay Ginther, MD
This weekend is Aunt Henrietta’s 90th birthday. I have just the right gift for her, Adora Premium Chocolates. My Aunt Henrietta has been our posterchild since the beginning of Cedar Valley Bone Health Institute of Iowa. Her adventures are well chronicled.
I had to tell her Endocrinologist about the Anabolic, Forteo. She agreed to give herself a daily shot. Then she proved that treatment had worked by falling down the stairs and not breaking anything.
Finally she locked in the gains of Forteo by starting the Antiresorptive that gets along with her severe GERD and aging kidneys, Prolia.
She can live alone in her own home because she Took Control of her bone health, with Calcium, Vitamin D3, Protein, Multiple Vitamins and Minerals, and Osteoporosis Medications. They are all necessary.
Happy Birthday Aunt Henrietta!
Jay Ginther, MD
Aromatase Inhibitors (AI) do a great job treating Breast Cancers which are Estrogen dependent. The AI wipe out all Estrogen thereby depriving the breast cancer of a needed stimulus.
Unfortunately, Aromatase Inhibitor treatment will also do considerable damage to your bones unless you take medication to protect your bones. The good news is that we have medication which can completely offset the harm AI treatment could do to your bones. But, you have to take it, and the sooner you start, the better.
Prolia (Denosumab for Osteoporosis) is specifically approved by the FDA for use in patients using Aromatase Inhibitors (AI) for their breast cancer. Prolia is specifically for women without metastases. Prolia can delay and/or prevent matastases when given early. Xgeva (Denosumab for Cancer) is used if metastases are already present.