Posts Tagged ‘Osteoporosis medication’

The American Society of Clinical Oncology received bad news about Breast Cancer Patients this week.  A study of women with breast cancer, being treated with Aromatase Inhibitors (AI), was presented at the 2014 Breast Cancer Symposium.  AI is a great treatment for breast cancer, however…

AI is known to decrease bone strength and to increase Fracture Risk.  How many of these patients  were evaluated for their bone health?  Only 54%.  How many got a repeat evaluation to check to be sure that their bone health was not deteriorating?  Only 46%.

Of those tested, 43% had a DXA T-score in the “osteopenia” range.  In this situation, FRAX is needed to calculate Fracture Risk.  41% of this group met guidelines for treatment with medication to prevent bone loss and Fractures.  Of those who should have been treated, only 23% were.

Aunt Henrietta – A Triumph

September 6, 2014 @ 8:48 pm
posted by Dr Ginther

Aunt Henrietta’s 90th birthday party was a triumph.  Over 100 friends, neighbors, and relatives attended.  She planned and arranged it all herself.  This was not the feeble 89 year old of last fall.  This was the comeback kid.

6 years ago Henrietta had fallen and broken both wrists and a shoulder in 3 separate incidents.  That was before she took Forteo, followed by Prolia.  Last year she was sick enough to be falling several times a day.  But she did not break anything!  Had she broken she would probably not have celebrated her 90th.

Aunt Henrietta waited until age 83 to start taking enough Calcium (Adora Premium Chocolates), enough Vitamin D, and almost enough Protein. Then she waited until she had fractured both wrists and a shoulder before starting osteoporosis medication.

I am not happy that she still falls ocassionally in her 3 level house, but I know that now she doesn’t break anything.

Aunt Henrietta is a triumph.

You don’t have to wait as long as she did to check up on your bone health.  Get a Complete Bone Health Evaluation.

Take Control of your future now.

Jay Ginther, MD

Aunt Henrietta’s Birthday

August 28, 2014 @ 9:11 pm
posted by Dr Ginther

This weekend is Aunt Henrietta’s 90th birthday.  I have just the right gift for her, Adora Premium Chocolates.  My Aunt Henrietta has been our posterchild since the beginning of Cedar Valley Bone Health Institute of Iowa.  Her adventures are well chronicled.

First, she broke one wrist when she was thrown down by a throw rug.  Then she broke the other wrist when her bifocals did her in.  Then she broke her shoulder when she thought all the ice had melted.

I had to tell her Endocrinologist about the Anabolic, Forteo.  She agreed to give herself a daily shot.  Then she proved that treatment had worked by falling down the stairs and not breaking anything.

Finally she locked in the gains of Forteo by starting the Antiresorptive that gets along with her severe GERD and aging kidneys, Prolia.

She can live alone in her own home because she Took Control of her bone health, with Calcium, Vitamin D3, Protein, Multiple Vitamins and Minerals, and Osteoporosis Medications.  They are all necessary.

Happy Birthday Aunt Henrietta!

Jay Ginther, MD

Enteric Coated Atelvia

July 29, 2014 @ 7:57 pm
posted by Dr Ginther

The biggest problem with oral Bisphosphonates is GI upset, especially Gastro-Esophogeal Reflux Disease (GERD).  Another problem is that you must take them on an empty stomach – then eat nothing for 30 to 60 minutes.  Atelvia attempts to evade those issues with enteric coating.  Atelvia is Risedronate (Actonel) which does not disolve until in the small intestines.  It can be taken with food.  This is definitely more convenient.

Published studies show Atelvia to be as effective in decreasing fracture rates as daily Actonel (the orginal dosing of Risedronate).  That is good.

The enteric coating should make GERD much less common than with regular Actonel.  Surprisingly, there are no published studies to back up that obvious supposition.  Nor are there any studies about other GI problems common with regular bisphosphonates.  Fortunately, we do have some samples for patients to try in order to determine if they have any GI problems with Atelvia, before getting a paid-for prescription.

Atelvia is still new enough on the market that we have no long term experience.  It may acquire the niche market for an oral Bisphosphonate without GERD.

Having an additional osteoporosis medication option is good.

Jay Ginther, MD