Posts Tagged ‘FRAX’

Forteo is a daily shot.  That is a nuicence, but a small price to pay for the only Anabolic, the only osteoporosis medication which will increase bone mass in spongy (cancellous) bone.  Diabetics give themselves a daily shot for the rest of their lives.  Forteo is for only 2 years and uses a tiny insulin needle. 

People worry about the warning that lab rats got Osteosarcoma after being given very high doses of Teriparatide for the equivalent of 70 human years.  We have not seen this in humans, or chimps, or monkeys, or dogs.  Rats have bones that grow all their lives.  We do not give Forteo to growing humans, pregnant women, nursing women, persons with Paget’s Disease or unexplained elevated Alkaline Phosphatase, or persons who have had radiation to their bones.

Remember that you must take adequate Calcium, with food, spread out over 3 meals. You must take enough Vitamin D3 to be able to absorb Calcium.  You must eat enough Protein for your OsteoBlasts to make new bone matrix.

The American Society of Clinical Oncology received bad news about Breast Cancer Patients this week.  A study of women with breast cancer, being treated with Aromatase Inhibitors (AI), was presented at the 2014 Breast Cancer Symposium.  AI is a great treatment for breast cancer, however…

AI is known to decrease bone strength and to increase Fracture Risk.  How many of these patients  were evaluated for their bone health?  Only 54%.  How many got a repeat evaluation to check to be sure that their bone health was not deteriorating?  Only 46%.

Of those tested, 43% had a DXA T-score in the “osteopenia” range.  In this situation, FRAX is needed to calculate Fracture Risk.  41% of this group met guidelines for treatment with medication to prevent bone loss and Fractures.  Of those who should have been treated, only 23% were.

“Baby-Boomers” Should Check Their Bones

June 6, 2014 @ 6:26 am
posted by Dr Ginther

A patient had no idea why her doc sent her to me for a Complete Bone Health Evaluation.  As a “baby-boomer”, she lives by the motto: “You are only as old as you choose to be.”  And she chooses to remain young.  If only it were possible…..

“I can’t have Osteoporosis.  I used to drink milk.  I am active and I plan to stay active!!!  So I just can’t have Osteoporosis!”  Unfortunately, she does have Osteoporosis by BMD on her DXA, by the multiple Vertebral Fractures on VFA, and by FRAX.  Still, there are simple steps to rescue her Bone Health before she Fractures.

Identify Fracture Risk – Prevent Fractures

April 23, 2014 @ 5:25 am
posted by Dr Ginther

Tomorrow I am at the 2014 National Osteoporosis Foundation meeting.  Actually the name “National Prevent Fractures Organization” would better explain our goals.  We don’t care about Osteoporosis as much as we care about Preventing Fractures.

DXA and T-score  test results of “osteoporosis” only identify about 15% of the persons who will fracture.  How can we identify those persons with “osteopenia” who will fracture?  We use FRAX and Vertebral Fracture Assessment (VFA).  My Poster # 18 tomorrow and Friday documents how adding VFA to DXA identifies additional persons at high risk for Fractures.