Posts Tagged ‘Forteo’

Aunt Henrietta Beat Osteoporosis at 90

June 1, 2015 @ 9:12 pm
posted by Dr Ginther

Aunt Henrietta enjoys her independent life at 90.  Especially when compared to how she was 4 years ago!

I visited her while out east for NOF.  She easily walked the 3 blocks to and from church.  She led the procession up and down every aisle in the huge Shoprite and the Rite-Aid, while stocking up on provisions for the month.  She even strolled more than 1/4 mile across the Delaware River pedestrian bridge.

She lives alone in a 2 story house.  I am not happy about the stairs, but she does not fall too often, and has not broken anything in 4 years.

Before Aunt Henrietta started treating her osteoporosis aggressively, she was rightfully terrified to do anything.  She was talking about dying in her house.  She had broken one wrist, then the other wrist, then her shoulder, in 3 separate falls.  Her plight and response has been an inspiration in my efforts for bone health.

She started Adora Chocolates (she loves dark) for Calcium, then added high dose Vitamin D.  I harrassed her into eating more protein.  But when she fell, she broke.  Her Quality of life was in the Dumpster.  Time for drastic action!

I talked her into the Anabolic, Forteo.  She failthfully gave herself a shot every day for 2 years.  Because of her aging kidneys, I followed with Prolia.  She has worked hard on proper nutrition.  She was determined to regain her Independence.  She succeeded.

Aunt Henrietta resurrected her Quality of Life.  She is stronger, more active, stubbornly Independent, and Fracture Free!  At age 90, that is everything.

Aunt Henrietta beat her osteoporosis!  You can too.

Find out what you need to correct with a Complete Bone Health Evaluation.

Take Control to Avoid Fractures and remain Independent.

Jay Ginther, MD

Osteoporosis Medications Reviewed

February 9, 2015 @ 6:32 pm
posted by Dr Ginther

Recently a patient asked me to review all osteoporosis medications for her to consider and choose from.  We had already optimized her Calcium intake, 25-hydroxy Vitamin D level, Protein intake, Multiple Vitamins & Minerals, and Exercise program.  These had all helped substantially, but not enough for her peace of mind.  She feels that she needs osteoporosis medication too.  Here they are:

Forteo is a daily shot.  That is a nuicence, but a small price to pay for the only Anabolic, the only osteoporosis medication which will increase bone mass in spongy (cancellous) bone.  Diabetics give themselves a daily shot for the rest of their lives.  Forteo is for only 2 years and uses a tiny insulin needle. 

People worry about the warning that lab rats got Osteosarcoma after being given very high doses of Teriparatide for the equivalent of 70 human years.  We have not seen this in humans, or chimps, or monkeys, or dogs.  Rats have bones that grow all their lives.  We do not give Forteo to growing humans, pregnant women, nursing women, persons with Paget’s Disease or unexplained elevated Alkaline Phosphatase, or persons who have had radiation to their bones.

Remember that you must take adequate Calcium, with food, spread out over 3 meals. You must take enough Vitamin D3 to be able to absorb Calcium.  You must eat enough Protein for your OsteoBlasts to make new bone matrix.

Forteo Increases Bone Thickness on the Inside

October 9, 2014 @ 5:19 pm
posted by Dr Ginther

Forteo (Teriparatide) increases the thickness of the struts making up spongy (cancellous) bone.  Forteo is the only osteoporosis medication to do that.  It also makes the hard outer shell (cortical bone) thicker.  How?  Forteo stimulates OsteoBlasts.  They make bone matrix, the collagen protein that is more than 80% of bone.

Forteo also stimulates bone turnover.  Healthy bone is constantly being resorbed and replaced.  This allows bone to eliminate the micro-cracks that gradually accumulate with activity.  Bone is strongest when it is a mixture of older more calcified (stiffer) material mixed thoroughly with younger less calcified (somewhat bendable) material.  Cracks cannot enlarge.  Strength is better.  More force is required to fracture the bone.