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Posts Tagged ‘anabolic’

If you fracture, your risk of a second fracture within a year is 3 to 5 times as great!  If that first or second fracture is a hip, you have a 25% chance of dying and a 25% chance of spending the rest of your life in a nursing home.  Scary.

Sometimes nutrition and lifestyle changes are enough.  Often medications are needed to effect real improvement.  The anabolic medications Teriparatide (Forteo), Abaloparatide (Tymlos), and Romosozumab (Evenity) not only prevent further fractures by increasing bone mass, but also speed healing.  The antiresorptive medications decrease fracture risk by preventing bone loss.

The NOF video at https://vimeo.com/267839997 discusses the likelihood of benefit in relation to the very small risk of harm from antiresorptive medications.

Understand the relative risks of taking a medication compared to the relative risks involved in not taking a medication.

Jay Ginther, MD

Iowa Bone Club 2020 Postponed

March 13, 2020 @ 9:43 am
posted by Dr Ginther

We are cancelling Iowa Bone Club for 24 April

We plan to reschedule for September, assuming that COVID-19 will have receded by then

Jay Ginther, MD

Iowa Bone Club 2020 – Friday 24 April

March 2, 2020 @ 1:09 pm
posted by Dr Ginther

Iowa Bone Club 2020 will meet at Allen College in Waterloo, IA on Friday 24 April.  This is the only meeting in Iowa each year which is dedicated solely to optimizing Bone Health.  We prefer to prevent unnecessary fractures.

We aim primarily at teaching healthcare professionals of all types about the latest advances in caring for bone health.  NPs, PAs, DNPs, RNs, LPNs, CMAs, Meds, DOs are all included.  Often the lecturers learn as much as the students.  CME and CEU credits will be available.

This year’s meeting will include a presentation about using anabolic medications to grow bones first, then preserve the gains.  We will discuss how optimizing bone quality before total joint replacement or spinal fusion results in faster healing and better results.  We will learn how to minimize the ill effects of common diseases like diabetes on bone health.

As always, we will have a roundtable for staff dealing with insurance companies about medication pre-authorizations.  Also our roundtable among providers sharing thoughts about difficult cases.

Full details will follow

Jay Ginther, MD

 

Improve Bone First – Preserve Bone Second

December 8, 2019 @ 8:19 pm
posted by Dr Ginther

National Bone Health treatment goals are changing for those patients with high fracture risk.  Simply preserving bones already at a too high fracture risk never made much sense to this former orthopedic surgeon.  Now the national leadership is stressing the need to lower fracture risk first, then preserve bones at a lower level of fracture risk.

We now have 3 anabolic medications which substantially lower fracture risk by increasing the thickness and strength of bone structure: Teriparatide (Forteo), Abaloparitide (Tymlos), and Romosozumab (Evenity).  They all decrease fracture risk substantially more than the antiresorptive (preserving) medications alone.  The difference in fracture risk grows for up to 5 years.  After that the difference in fracture risk between anabolic meds followed by preserving meds vs. preserving meds alone remains the same.

Calcium can take up to 3 additional years to collect in newly formed bone matrix.  DXA shows calcium in bone (Bone Mineral Density).   Much of the increased BMD can only be seen on DXA after the anabolic med is completed and the antiresorptive med is started.

All of the anabolic medications must be followed by antiresorptive medication to preserve the gains made by the anabolic.  No medication to grow or preserve bone can work without adequate nutrition in the form of absorbable calcium, vitamin D3, protein and other vitamins and minerals.

Jay Ginther, MD