Osteoclasts are the cells that eat away bone. Osteoclasts are normally kept under control by Estrogen in women and Testosterone in men. Women suddenly lose Estrogen at Menopause. Men gradually lose Testosterone over time. Osteoclasts are like misbehaving teenagers. Once the control is lost, it is “Osteoclasts Gone Wild”.
The U.S. Preventive Services Task Force has released new guidelines for screening for Osteoporosis by using DXA to test for Bone Mineral Density. These are more restrictive than current National Osteoporosis Foundation guidelines and may predict cutbacks in covered services coming under “Obamacare” which is scheduled to cut Medicare spending by 30 per cent over the next 10 years.
Antiresorptives are the most common and best known Osteoporosis medications. Antiresorptives slow down the Osteoclasts. They target the Osteoclasts and prevent them from eating away (resorbing) the bone. They come in several varieties.