All three kids were home this weekend along with both grandkids. That put us in a Blue Zone.
One year old Gwen was showing off that she can walk by herself – especially when she had an audience to cheer her on. Three weeks ago she could manage only a few steps at a time. Now she can walk across a room. Amazing difference! Until you realize that she took 5% of her lifetime to learn that new trick.
Almost 4 year old RJ is a perpetual motion machine. Saturday he went out with his uncles (both starting sweepers in high school) and came home with a complete soccer outfit for his classes starting Monday. He tore around the yard with them kicking the ball ahead of him. Under duress he took off the cletes and shin guards for bed. More running at the family picnic today with his cousins. He is sleeping in the car heading back to MN in the entire outfit. Good thing his car seat is in the back and downwind.
Engagement party last evening, for son Greg and his fiance Erika, gave them the opportunity to see our friends who knew him in HS. He is certainly not a kid any more. In fact he and his siblings are all in their thirties. When did I get old enough to have kids that old?
Family is a Blue Zone.
Jay Ginther, MD
Bisphosphonates accumulate in your bone. When OsteoClasts gobble up your bone, bisphosphonates are released into the Osteoclasts and disable or kill the Osteoclasts. This is great news when the problem is Osteoclasts Gone Wild. Bisphosphonates preserve bone by slowing down bone resorption. However, after a few months, bone formation by OsteoBlasts also slows down, resulting in slow bone turnover.
Moderate and balanced bone turnover is good. You repair microcracks in your bone when OsteoClasts resorb the bone around them and OsteoBlasts fill in the void with new bone matrix. A mix of new and old bone is far stronger than all old bone. Some OsteoClast activity is necessary to heal fractures, especially incomplete (stress) fractures. That is where long term bisphosphonates can be too much of a good thing.
Bisphosphonates are the most commonly prescribed Antiresorptive medications used to prevent or treat Ostoeporosis. We know them as Fosamax (Alendronate), Boniva (Ibandronate), Actonel (Risendronate), Atelvia (enteric coated Risendronate), and IV Reclast (Zolendronate). All but the last are pills taken weekly or monthly.
If your bone is strong enough that preserving it is sufficient to prevent fractures, then Antiresorptive medication is what you need. If you are able to follow the protocol of taking the pill on an empty stomach, followed by one or more full glasses of plain water, and eating or drinking nothing else for at least 30 minutes (60 for Boniva) while remaining upright, Oral Bisphosphonates are the medication for you.
July 4th 1776 saw the publication of a Declaration of Independence from the Britain, written and approved by radical idealists in Philadelphia. The ideas and ideals expressed were revolutionary then, and still are today.
Each human being is endowed with the right to life, liberty and the pursuit of individual success. Those rights come not from King, or Parliament, or President, or Congress. Those rights come from the Creator and are an essential fact of human existence. Incredible!